Table of Contents
Cells, Volume 6, Issue 3 (September 2017)
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Cover Story (view full-size image) Autophagy cytoplasmic quality control protects neurons against operational stress and cell death. [...] Read more. Autophagy cytoplasmic quality control protects neurons against operational stress and cell death. Human neurodegenerative diseases are often associated with declining autophagic activity, highlighting the need for better human neuronal disease models. Human neurons can be generated from somatic cells following pluripotency reprogramming (hiPSCs) and neural induction. Here, we discuss the potential of hiPSC-derived neurons for autophagy research in human neurodegenerative disease models in vitro. View this paper