Next Article in Journal
Smart Sensor Systems for Wearable Electronic Devices
Next Article in Special Issue
Microstructural and Mechanical Implications of Microscaled Assembly in Droplet-based Multi-Material Additive Manufacturing
Previous Article in Journal
Synthesis and Phase Transition of Poly(N-isopropylacrylamide)-Based Thermo-Sensitive Cyclic Brush Polymer
Previous Article in Special Issue
Material Evaluation and Process Optimization of CNT-Coated Polymer Powders for Selective Laser Sintering
Article Menu
Issue 7 (July) cover image

Export Article

Open AccessArticle
Polymers 2017, 9(7), 302; doi:10.3390/polym9070302

Two-Photon-Induced Microstereolithography of Chitosan-g-Oligolactides as a Function of Their Stereochemical Composition

1
Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences, 70 Profsoyuznaya str., Moscow 117393, Russia
2
Institute of Photonic Technologies, Research center “Crystallography and Photonics”, Russian Academy of Sciences, 2 Pionerskaya str., Troitsk, Moscow 142190, Russia
3
Institute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia
4
Semenov Institute of Chemical Physics, Russian Academy of Sciences, 4 Kosygina str., Moscow 119334, Russia
*
Author to whom correspondence should be addressed.
Received: 12 June 2017 / Revised: 20 July 2017 / Accepted: 21 July 2017 / Published: 24 July 2017
(This article belongs to the Special Issue Three-Dimensional Structures: Fabrication and Application)
View Full-Text   |   Download PDF [4898 KB, uploaded 24 July 2017]   |  

Abstract

Chitosan-g-oligolactide copolymers with relatively long oligolactide grafted chains of various stereochemical compositions have been synthetized via a solvent-free mechanochemical technique and tailored to fabricate three-dimensional hydrogels using two-photon induced microstereolithography. An effect of the characteristics of chitosan and oligolactide used for the synthesis on the grafting yield and copolymer’s behavior were evaluated using fractional analysis, FTIR-spectroscopy, dynamic light scattering, and UV-spectrophotometry. The lowest copolymer yield was found for the system based on chitosan with higher molecular weight, while the samples consisting of low-molecular weight chitosan showed higher grafting degrees, which were comparable in both the cases of l,l- or l,d-oligolactide grafting. The copolymer processability in the course of two-photon stereolithography was evaluated as a function of the copolymer’s characteristics and stereolithography conditions. The structure and mechanical properties of the model film samples and fabricated 3D hydrogels were studied using optical and scanning electron microscopy, as well as by using tensile and nanoindenter devices. The application of copolymer with oligo(l,d-lactide) side chains led to higher processability during two-photon stereolithography in terms of the response to the laser beam, reproduction of the digital model, and the mechanical properties of the fabricated hydrogels. View Full-Text
Keywords: laser stereolithography; chitosan; lactide; mechanochemistry; two-photon polymerization; graft-copolymers; hydrogels laser stereolithography; chitosan; lactide; mechanochemistry; two-photon polymerization; graft-copolymers; hydrogels
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Demina, T.S.; Bardakova, K.N.; Minaev, N.V.; Svidchenko, E.A.; Istomin, A.V.; Goncharuk, G.P.; Vladimirov, L.V.; Grachev, A.V.; Zelenetskii, A.N.; Timashev, P.S.; Akopova, T.A. Two-Photon-Induced Microstereolithography of Chitosan-g-Oligolactides as a Function of Their Stereochemical Composition. Polymers 2017, 9, 302.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top