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Polymers 2017, 9(7), 265; https://doi.org/10.3390/polym9070265

Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching

1
Key Laboratory for Biomedical Engineering of Education, Ministry of China, Hangzhou 310027, China
2
Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Zhejiang University, Hangzhou 310027, China
3
Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK
4
Department of Mechanical Engineering, University College London, London WC1E 7JE, UK
*
Author to whom correspondence should be addressed.
Academic Editor: Mohamed Khayet
Received: 22 May 2017 / Revised: 28 June 2017 / Accepted: 28 June 2017 / Published: 3 July 2017
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Abstract

Topography and microstructure engineering are rapidly evolving areas of importance for biomedical and pharmaceutical remits. Here, PVA (Polyvinyl alcohol) microbubbles (diameter range ~126 to 414 μm) were used to fabricate beaded (beads-on) nanofibers using an electrohydrodynamic atomization (EHDA) technique. Mean fiber diameter, inter-bead distance, and aspect ratio (AR) were investigated by regulating EHDA process parameters. PVA fibers (diameter range ~233 to 737 nm) were obtained possessing bead ARs in the range of ~10 to 56%. AR was used to modulate hydrophilicity and active release. View Full-Text
Keywords: bubble; beaded nanofibers; electrospinning; polyvinyl alcohol bubble; beaded nanofibers; electrospinning; polyvinyl alcohol
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Yao, Z.-C.; Yuan, Q.; Ahmad, Z.; Huang, J.; Li, J.-S.; Chang, M.-W. Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching. Polymers 2017, 9, 265.

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