Next Article in Journal
Block Co-Polymers for Nanolithography: Rapid Microwave Annealing for Pattern Formation on Substrates
Previous Article in Journal
Chitosan: Gels and Interfacial Properties
Article Menu

Export Article

Open AccessArticle
Polymers 2015, 7(3), 580-591; doi:10.3390/polym7030580

Keratin/Polyvinyl Alcohol Blend Films Cross-Linked by Dialdehyde Starch and Their Potential Application for Drug Release

1
School of Materials Science and Engineering, Northwestern Polytechnical University, Xian 710072, Shanxi, China
2
Green Chemical Engineering Institute, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, Guangdong, China
3
Guangzhou Vocational College of Science and Technology, Guangzhou 510550, Guangdong, China
4
School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton BN2 4GJ, UK
*
Author to whom correspondence should be addressed.
Academic Editors: João F. Mano and Ernst Wagner
Received: 20 December 2014 / Revised: 6 February 2015 / Accepted: 15 February 2015 / Published: 23 March 2015
View Full-Text   |   Download PDF [1414 KB, uploaded 23 March 2015]   |  

Abstract

Feather keratin (FK) extracted from feathers represents a valuable source of biodegradable and biocompatible polymer. The aim of this study was the development and characterization of blended films based on FK and polyvinyl alcohol (PVA) cross-linked by dialdehyde starch (DAS) for a potential drug release application. The compatibility of FK/PVA was improved when cross-linked by DAS: the relative crystallinity of the PVA/FK film slightly decreased, and the enthalpy value for the melting peak decreased by about 50% for the cross-linked films. The total soluble mass of all blend films in water was below 35% at 37 °C, indicating a good stability of the films in water. The results of the Rhodamine B dye (as a model drug) release tests showed that the release rates decreased with increasing DAS content. DAS-induced cross-linking improves several important properties of the FK/PVA films, such as the compactness, the compatibility, and the stability in water. These improvements offer the potential to expand the application of FK films in the biomaterial field. View Full-Text
Keywords: feather keratin; PVA; dialdehyde starch; degradable film; eco-friendly material feather keratin; PVA; dialdehyde starch; degradable film; eco-friendly material
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Dou, Y.; Zhang, B.; He, M.; Yin, G.; Cui, Y.; Savina, I.N. Keratin/Polyvinyl Alcohol Blend Films Cross-Linked by Dialdehyde Starch and Their Potential Application for Drug Release. Polymers 2015, 7, 580-591.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top