Effects of RAFT Agent on the Selective Approach of Molecularly Imprinted Polymers
AbstractTwo types of reversible addition-fragmentation chain transfer molecularly imprinted polymers (RAFT-MIPs) were synthesized using different monomers, which were methacrylic acid functionalized β-cyclodextrin (MAA-β-CD) and 2-hydroxyethyl methacrylate functionalized β-cyclodextrin (HEMA-β-CD), via reversible addition-fragmentation chain transfer (RAFT) polymerization, and were represented as RAFT-MIP(MAA-β-CD) and RAFT-MIP(HEMA-β-CD), respectively. Both RAFT-MIPs were systematically characterized using Fourier Transform Infrared Spectroscopy (FTIR), Field Emission Scanning Electron Microscopy (FESEM), Brunauer-Emmett-Teller (BET), and rebinding experimental study. The results were compared with MIPs synthesized via the traditional radical polymerization (TRP) process, and were represented as MIP(MAA-β-CD) and MIP(HEMA-β-CD). Morphology results show that RAFT-MIP(MAA-β-CD) has a slightly spherical feature with a sponge-like form, while RAFT-MIP(HEMA-β-CD) has a compact surface. BET results show that the surface area of RAFT-MIP(MAA-β-CD) is higher than MIP(MAA-β-CD), while the RAFT-MIP(HEMA-β-CD) surface area is lower than that of MIP(HEMA-β-CD). Rebinding experiments indicate that the RAFT agent increased the binding capacity of RAFT-MIP(MAA-β-CD), but not of RAFT-MIP(HEMA-β-CD), which proves that a RAFT agent does not always improve the recognition affinity and selective adsorption of MIPs. The usability of a RAFT agent depends on the monomer used to generate potential MIPs. View Full-Text
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Asman, S.; Mohamad, S.; Sarih, N.M. Effects of RAFT Agent on the Selective Approach of Molecularly Imprinted Polymers. Polymers 2015, 7, 484-503.
Asman S, Mohamad S, Sarih NM. Effects of RAFT Agent on the Selective Approach of Molecularly Imprinted Polymers. Polymers. 2015; 7(3):484-503.Chicago/Turabian Style
Asman, Saliza; Mohamad, Sharifah; Sarih, Norazilawati M. 2015. "Effects of RAFT Agent on the Selective Approach of Molecularly Imprinted Polymers." Polymers 7, no. 3: 484-503.