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Polymers 2015, 7(2), 186-219; doi:10.3390/polym7020186

Multifunctional Nanofibers towards Active Biomedical Therapeutics

Department of Chemistry and Biochemistry, Lamar University, P.O. Box 10009, Beaumont, TX 77710, USA
Materials Engineering And Nanosensor (MEAN) Laboratory, Dan F. Smith Department of Chemical Engineering, Lamar University, P.O. Box 10053, Beaumont, TX 77710, USA
Integrated Composites Laboratory (ICL), Dan F. Smith Department of Chemical Engineering, Lamar University, P.O. Box 10053, Beaumont, TX 77710, USA
Authors to whom correspondence should be addressed.
Academic Editor: Russell Gorga
Received: 8 November 2014 / Revised: 11 December 2014 / Accepted: 23 January 2015 / Published: 3 February 2015
View Full-Text   |   Download PDF [5125 KB, uploaded 3 February 2015]   |  


One-dimensional (1-D) nanostructures have attracted enormous research interest due to their unique physicochemical properties and wide application potential. These 1-D nanofibers are being increasingly applied to biomedical fields owing to their high surface area-to-volume ratio, high porosity, and the ease of tuning their structures, functionalities, and properties. Many biomedical nanofiber reviews have focused on tissue engineering and drug delivery applications but have very rarely discussed their use as wound dressings. However, nanofibers have enormous potential as wound dressings and other clinical applications that could have wide impacts on the treatment of wounds. Herein, the authors review the main fabrication methods of nanofibers as well as requirements, strategies, and recent applications of nanofibers, and provide perspectives of the challenges and opportunities that face multifunctional nanofibers for active therapeutic applications. View Full-Text
Keywords: multifunctional; nanofibers; biomedical; therapeutics; electrospun; clinical multifunctional; nanofibers; biomedical; therapeutics; electrospun; clinical

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Sharma, J.; Lizu, M.; Stewart, M.; Zygula, K.; Lu, Y.; Chauhan, R.; Yan, X.; Guo, Z.; Wujcik, E.K.; Wei, S. Multifunctional Nanofibers towards Active Biomedical Therapeutics. Polymers 2015, 7, 186-219.

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