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Polymers 2014, 6(8), 2100-2115; doi:10.3390/polym6082100

Polyelectrolyte Multilayers in Microfluidic Systems for Biological Applications

1 Dakota Consulting Inc., 1110 Bonifant Street, Suite 310, Silver Spring, MD 20910, USA 2 Electrical & Computer Engineering Department, George Mason University, 4400 University Drive, Fairfax, VA 22030, USA 3 Physical Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA
* Author to whom correspondence should be addressed.
Received: 22 May 2014 / Revised: 15 July 2014 / Accepted: 22 July 2014 / Published: 31 July 2014
(This article belongs to the Special Issue Polyelectrolytes 2014)
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The formation of polyelectrolyte multilayers (PEMs) for the first time, two decades ago, demonstrating the assembly on charged substrates in a very simple and efficient way, has proven to be a reliable method to obtain structures tunable at the nanometer scale. Much effort has been put into the assembly of these structures for their use in biological applications. A number of these efforts have been in combination with microfluidic systems, which add to the nanoassembly that is already possible with polyelectrolytes, a new dimension in the construction of valuable structures, some of them not possible with conventional systems. This review focuses on the advancements demonstrated by the combination of PEMs and microfluidic systems, and their use in biological applications.
Keywords: polyelectrolyte multilayers; microfluidics; lab-on-a-chip; biological applications polyelectrolyte multilayers; microfluidics; lab-on-a-chip; biological applications
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Minnikanti, S.; Gangopadhyay, A.; Reyes, D.R. Polyelectrolyte Multilayers in Microfluidic Systems for Biological Applications. Polymers 2014, 6, 2100-2115.

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