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Polymers 2014, 6(2), 515-551; doi:10.3390/polym6020515
Review

Peptide-Based Polymer Therapeutics

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Received: 28 December 2013; in revised form: 6 February 2014 / Accepted: 7 February 2014 / Published: 21 February 2014
(This article belongs to the Special Issue Polymers for Drug Delivery)
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Abstract: Polypeptides are envisaged to achieve a major impact on a number of different relevant areas such as biomedicine and biotechnology. Acquired knowledge and the increasing interest on amino acids, peptides and proteins is establishing a large panel of these biopolymers whose physical, chemical and biological properties are ruled by their controlled sequences and composition. Polymer therapeutics has helped to establish these polypeptide-based constructs as polymeric nanomedicines for different applications, such as disease treatment and diagnostics. Herein, we provide an overview of the advantages of these systems and the main methodologies for their synthesis, highlighting the different polypeptide architectures and the current research towards clinical applications.
Keywords: polymer therapeutics; polypeptides; drug delivery; nanomedicine polymer therapeutics; polypeptides; drug delivery; nanomedicine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Duro-Castano, A.; Conejos-Sánchez, I.; Vicent, M.J. Peptide-Based Polymer Therapeutics. Polymers 2014, 6, 515-551.

AMA Style

Duro-Castano A, Conejos-Sánchez I, Vicent MJ. Peptide-Based Polymer Therapeutics. Polymers. 2014; 6(2):515-551.

Chicago/Turabian Style

Duro-Castano, Aroa; Conejos-Sánchez, Inmaculada; Vicent, María J. 2014. "Peptide-Based Polymer Therapeutics." Polymers 6, no. 2: 515-551.


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