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Polymers 2018, 10(1), 100; https://doi.org/10.3390/polym10010100

Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization

1
Department of Chemistry, College of Science, and Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University, Yanji 133002, China
2
Department of Applied Organic Materials Engineering, Inha University, Incheon 402-751, Korea
3
Department of General Education, Kookmin University, Seoul 02707, Korea
*
Authors to whom correspondence should be addressed.
Received: 10 December 2017 / Revised: 16 January 2018 / Accepted: 17 January 2018 / Published: 20 January 2018
(This article belongs to the Special Issue Polymer Based Bio-Sensors)
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Abstract

The use of low-dimensional inorganic or organic nanomaterials has advantages for DNA and protein recognition due to their sensitivity, accuracy, and physical size matching. In this research, poly(3-methylthiophene) (P3MT) nanowires (NWs) are electrochemically prepared with dopant followed by functionalization with probe DNA (pDNA) sequence through electrostatic interaction. Various lengths of pDNA sequences (10-, 20- and 30-mer) are conjugated to the P3MT NWs respectively followed with hybridization with their complementary target DNA (tDNA) sequences. The nanoscale photoluminescence (PL) properties of the P3MT NWs are studied throughout the whole process at solid state. In addition, the correlation between the PL enhancement and the double helix DNA with various lengths is demonstrated. View Full-Text
Keywords: poly(3-methylthiophene); nanowire; DNA length; nanoscale photoluminescence poly(3-methylthiophene); nanowire; DNA length; nanoscale photoluminescence
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Huang, J.; Choi, J.; Lee, G.S.; Chen, F.; Cui, C.; Jin, L.Y.; Park, D.H. Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization. Polymers 2018, 10, 100.

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