Next Article in Journal
[Pr2(pdc)3(Hpdc)(H2O)4]n·n(H3hp)·8n(H2O), a One-Dimensional Coordination Polymer Containing PrO6N3 Tri-Capped Trigonal Prisms and PrO8N Mono-Capped Square Anti-Prisms (H2pdc = Pyridine 2,6-Dicarboxylic Acid, C7H5NO4; 3hp = 3-Hydroxy Pyridine, C5H5NO)
Previous Article in Journal
Crystal and Molecular Structure Studies of Ethyl 4-(4-Hydroxyphenyl)-6-(6-methoxy-2-naphthyl)-2-oxocyclohex-3-ene-1-carboxylate and Ethyl 4-(3-Bromophenyl)-6-(6-methoxy-2-naphthyl)-2-oxocyclohex-3-ene-1-carboxylate
Crystals 2012, 2(3), 1248-1252; doi:10.3390/cryst2031248
Short Note

One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate

1,* , 1
1 Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan 2 Department of Inorganic and Analytical Chemistry, Universität Paderborn, Warburgerstr. 100, D-33098, Paderborn, Germany
* Author to whom correspondence should be addressed.
Received: 15 May 2012 / Revised: 31 July 2012 / Accepted: 14 August 2012 / Published: 27 August 2012
View Full-Text   |   Download PDF [181 KB, uploaded 27 August 2012]   |   Browse Figures


The title compound, Methyl 5-Hydroxy-1-Phenyl-1H-Pyrazole-3-Carboxylate (C11H10N2O3), was prepared by a one-pot, two-component reaction of an equimolar mixture of phenyl hydrazine and dimethyl acetylene dicarboxylate (DMAD) at reflux temperature for 2 h in a mixture of toluene and dichloromethane as solvent. C11H10N2O3 was crystallized from an ethanol solution in monoclinic space group P21/c with unit cell dimensions a = 9.5408(16), b = 9.5827(16), c = 11.580(2) Å, β = 105.838(3)°, V = 1018.5(3) Å3, Z = 4.
Keywords: pyrazole; methyl 5-hydroxy-1-phenyl-1H-pyrazole-3-carboxylate; crystal structure pyrazole; methyl 5-hydroxy-1-phenyl-1H-pyrazole-3-carboxylate; crystal structure
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary material

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Saeed, A.; Arshad, I.; Flörke, U. One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate. Crystals 2012, 2, 1248-1252.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Crystals EISSN 2073-4352 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert