The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole

doi:10.3390/cryst2020176

This article is

freely available
re-usable

Crystals 2012, 2(2), 176-181; doi:10.3390/cryst2020176

Communication

The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole

Kristin Ebert¹, Martin Köckerling² and Constantin Mamat^1,*

¹ Institut für Radiopharmazie, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, D 01328 Dresden, Germany ² Institut für Chemie, Anorganische Festkörperchemie, Albert-Einstein-Straße 3a, D-18059 Rostock, Germany

* Author to whom correspondence should be addressed.

Received: 23 December 2011; in revised form: 21 February 2012 / Accepted: 23 March 2012 / Published: 10 April 2012

Download PDF Full-Text [821 KB, Updated Version, uploaded 11 April 2012 14:01 CEST]

The original version is still available [231 KB, uploaded 10 April 2012 10:05 CEST]

Abstract: Two novel indazole derivatives protected with p-methoxybenzyl group were synthesized and characterized. The crystal and molecular structure of 2-(4-methoxybenzyl)-4-nitro-2H-indazole as one out of the two regioisomers is reported. The compound was obtained from a saturated petroleum ether/ethyl acetate mixture and crystallizes in the triclinic space group P`1. The unit cell parameters are: a = 6.8994(1) Å, b = 9.8052(2) Å, c = 11.1525(2) Å; α = 71.729(1)°, β = 79.436(1)°, γ = 74.349(1)° and V = 685.83(2) Å³. There are two independent molecules found in the asymmetric unit.

Keywords: indazoles; protecting group; p-methoxy benzyl; X-ray structure

Supplementary Files

Supplementary File 1:
CIF-Document (CIF, 13 KB)

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Ebert, K.; Köckerling, M.; Mamat, C. The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole. Crystals 2012, 2, 176-181.

AMA Style

Ebert K, Köckerling M, Mamat C. The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole. Crystals. 2012; 2(2):176-181.

Chicago/Turabian Style

Ebert, Kristin; Köckerling, Martin; Mamat, Constantin. 2012. "The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole." Crystals 2, no. 2: 176-181.

Crystals EISSN 2073-4352 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert