Aberrant Wnt Signaling in Leukemia
AbstractThe Wnt signaling pathway is essential in the development and homeostasis of blood and immune cells, but its exact role is still controversial and is the subject of intense research. The malignant counterpart of normal hematopoietic cells, leukemic (stem) cells, have hijacked the Wnt pathway for their self-renewal and proliferation. Here we review the multiple ways dysregulated Wnt signaling can contribute to leukemogenesis, both cell autonomously as well as by changes in the microenvironment. View Full-Text
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Staal, F.J.T.; Famili, F.; Garcia Perez, L.; Pike-Overzet, K. Aberrant Wnt Signaling in Leukemia. Cancers 2016, 8, 78.
Staal FJT, Famili F, Garcia Perez L, Pike-Overzet K. Aberrant Wnt Signaling in Leukemia. Cancers. 2016; 8(9):78.Chicago/Turabian Style
Staal, Frank J.T.; Famili, Farbod; Garcia Perez, Laura; Pike-Overzet, Karin. 2016. "Aberrant Wnt Signaling in Leukemia." Cancers 8, no. 9: 78.
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