Oncogenic MicroRNAs: Key Players in Malignant Transformation
AbstractMicroRNAs (miRNAs) represent a class of non-coding RNAs that exert pivotal roles in the regulation of gene expression at the post-transcriptional level. MiRNAs are involved in many biological processes and slight modulations in their expression have been correlated with the occurrence of different diseases. In particular, alterations in the expression of miRNAs with oncogenic or tumor suppressor functions have been associated with carcinogenesis, malignant transformation, metastasis and response to anticancer treatments. This review will mainly focus on oncogenic miRNAs whose aberrant expression leads to malignancy. View Full-Text
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Frixa, T.; Donzelli, S.; Blandino, G. Oncogenic MicroRNAs: Key Players in Malignant Transformation. Cancers 2015, 7, 2466-2485.
Frixa T, Donzelli S, Blandino G. Oncogenic MicroRNAs: Key Players in Malignant Transformation. Cancers. 2015; 7(4):2466-2485.Chicago/Turabian Style
Frixa, Tania; Donzelli, Sara; Blandino, Giovanni. 2015. "Oncogenic MicroRNAs: Key Players in Malignant Transformation." Cancers 7, no. 4: 2466-2485.