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Cancers 2013, 5(2), 519-528; doi:10.3390/cancers5020519
Review

Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect

1,* , 1, 1, 2, 3 and 1,*
Received: 4 March 2013; in revised form: 9 April 2013 / Accepted: 3 May 2013 / Published: 8 May 2013
(This article belongs to the Special Issue Soft Tissue and Bone Sarcoma)
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Abstract: There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.
Keywords: MPNST; neurofibromatosis; nerve sheath tumor; atypical neurofibroma; low grade MPNST MPNST; neurofibromatosis; nerve sheath tumor; atypical neurofibroma; low grade MPNST
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Bernthal, N.M.; Jones, K.B.; Monument, M.J.; Liu, T.; Viskochil, D.; Randall, R.L. Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect. Cancers 2013, 5, 519-528.

AMA Style

Bernthal NM, Jones KB, Monument MJ, Liu T, Viskochil D, Randall RL. Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect. Cancers. 2013; 5(2):519-528.

Chicago/Turabian Style

Bernthal, Nicholas M.; Jones, Kevin B.; Monument, Michael J.; Liu, Ting; Viskochil, David; Randall, R. L. 2013. "Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect." Cancers 5, no. 2: 519-528.


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