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Desmoid Tumors in Pregnant and Postpartum Women
Department of Medicine, University of Colorado Denver, Denver, CO 80045, USA
Department of Pharmacy, University of Colorado Denver, Denver, CO 80045, USA
Department of the Tumor Registry, University of Colorado Denver, Denver, CO 80045, USA
Department of Surgery, University of Colorado Denver, Denver, CO 80045, USA
* Authors to whom correspondence should be addressed.
Received: 4 January 2012; in revised form: 11 February 2012 / Accepted: 13 February 2012 / Published: 21 February 2012
Abstract: We report here a review of the current medical literature on pregnancy associated desmoids, including 10 cases of our own. The pertinent findings are that a large percentage of desmoids in females arise in and around pregnancy. Most occur in the abdominal muscles, particularly the right rectus abdominus, perhaps related to trauma from abdominal stretching and fetal movement. While these tumors may regress spontaneously after delivery most can be surgically resected with low recurrence rates even with R1 resections and this is clearly the treatment of choice. Subsequent pregnancies do not appear to result in recurrence in either FAP or non FAP patients. It is not clear from currently available data whether pregnancy associated desmoids are molecularly distinct from other desmoids.
Keywords: desmoid; pregnancy; post-partum; female
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MDPI and ACS Style
Robinson, W.A.; McMillan, C.; Kendall, A.; Pearlman, N. Desmoid Tumors in Pregnant and Postpartum Women. Cancers 2012, 4, 184-192.
Robinson WA, McMillan C, Kendall A, Pearlman N. Desmoid Tumors in Pregnant and Postpartum Women. Cancers. 2012; 4(1):184-192.
Robinson, William A.; McMillan, Colette; Kendall, Amy; Pearlman, Nathan. 2012. "Desmoid Tumors in Pregnant and Postpartum Women." Cancers 4, no. 1: 184-192.