Cancers 2009, 1(1), 12-20; doi:10.3390/cancers1010012
Article

Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC)

Sushil Beriwal 1,* email, Bunja Rungruang 2 email, Atilla Soran 3 email, Darcy Thull 4 email, Joseph L. Kelley 2 email, Rohit Bhargava 5 email, Chyongchiou J. Lin 6 email and Paniti Sukumvanich 2 email
1 Department of Radiation Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA 2 Department of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA 3 Department of Surgery, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA 4 Division of Hematology Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA 5 Department of Pathology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA 6 Department of Family Medicine, School of Medicine, University of Pittsburgh, 3518 Fifth Avenue, Pittsburgh, PA 15261, USA
* Author to whom correspondence should be addressed.
Received: 13 October 2009; in revised form: 23 November 2009 / Accepted: 25 November 2009 / Published: 4 December 2009
(This article belongs to the Special Issue Breast Cancer)
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Abstract: We have compared outcomes, including the locoregional recurrence, between mastectomy and breast conserving therapy in PABC. Patients were divided into those who were treated with mastectomies (group 1) and those with breast conserving surgery (group 2). The groups were comparable except for lower mean age in group 2 and more patients with stage III disease and higher number of nodes positive in the group 1. Five-year actuarial LRR, distant metastases free survival and overall survival in group 1 vs. 2 were 10% vs. 37%, 73% vs. 81% and 57% vs. 59% respectively. The patients with PABC treated with breast conserving therapy, despite having lower stage disease, have a higher risk of local regional recurrence in comparison with those treated with mastectomy.
Keywords: pregnancy; cancer; surgery; mastectomy; breast conserving surgery

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Cite This Article

MDPI and ACS Style

Beriwal, S.; Rungruang, B.; Soran, A.; Thull, D.; Kelley, J.L.; Bhargava, R.; Lin, C.J.; Sukumvanich, P. Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC). Cancers 2009, 1, 12-20.

AMA Style

Beriwal S, Rungruang B, Soran A, Thull D, Kelley JL, Bhargava R, Lin CJ, Sukumvanich P. Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC). Cancers. 2009; 1(1):12-20.

Chicago/Turabian Style

Beriwal, Sushil; Rungruang, Bunja; Soran, Atilla; Thull, Darcy; Kelley, Joseph L.; Bhargava, Rohit; Lin, Chyongchiou J.; Sukumvanich, Paniti. 2009. "Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC)." Cancers 1, no. 1: 12-20.

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