Next Article in Journal
A Horizontal Magnetic Tweezers and Its Use for Studying Single DNA Molecules
Previous Article in Journal
Fabrication of an Anti-Reflective and Super-Hydrophobic Structure by Vacuum Ultraviolet Light-Assisted Bonding and Nanoscale Pattern Transfer
Previous Article in Special Issue
Investigation on Surface Integrity of Rapidly Solidified Aluminum RSA 905 by Magnetic Field-Assisted Finishing
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessArticle
Micromachines 2018, 9(4), 187; doi:10.3390/mi9040187

Progress on the Use of Commercial Digital Optical Disc Units for Low-Power Laser Micromachining in Biomedical Applications

1
Facultad de Ciencias, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, Ciudad de Mexico CP 04500, Mexico
2
Laboratorio Nacional de Soluciones Biomiméticas para Diagnóstico y Terapia LaNSBioDyT, Facultad de Ciencias, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, Ciudad de Mexico CP 04500, Mexico
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 23 March 2018 / Revised: 2 April 2018 / Accepted: 3 April 2018 / Published: 16 April 2018
(This article belongs to the Special Issue Micro-Machining: Challenges and Opportunities)
View Full-Text   |   Download PDF [33659 KB, uploaded 18 April 2018]   |  

Abstract

The development of organ-on-chip and biological scaffolds is currently requiring simpler methods for microstructure biocompatible materials in three dimensions, to fabricate structural and functional elements in biomaterials, or modify the physicochemical properties of desired substrates. Aiming at addressing this need, a low-power CD-DVD-Blu-ray laser pickup head was mounted on a programmable three-axis micro-displacement system in order to modify the surface of polymeric materials in a local fashion. Thanks to a specially-designed method using a strongly absorbing additive coating the materials of interest, it has been possible to establish and precisely control processes useful in microtechnology for biomedical applications. The system was upgraded with Blu-ray laser for additive manufacturing and ablation on a single platform. In this work, we present the application of these fabrication techniques to the development of biomimetic cellular culture platforms thanks to the simple integration of several features typically achieved with traditional, less cost-effective microtechnology methods in one step or through replica-molding. Our straightforward approach indeed enables great control of local laser microablation or polymerization for true on-demand biomimetic micropatterned designs in transparent polymers and hydrogels and is allowing integration of microfluidics, microelectronics, surface microstructuring, and transfer of superficial protein micropatterns on a variety of biocompatible materials. View Full-Text
Keywords: laser micromachining; scaffold; biomimetics; microadditive manufacturing; microsubtractive manufacturing laser micromachining; scaffold; biomimetics; microadditive manufacturing; microsubtractive manufacturing
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Cruz-Ramírez, A.; Sánchez-Olvera, R.; Zamarrón-Hernández, D.; Hautefeuille, M.; Cabriales, L.; Jiménez-Díaz, E.; Díaz-Bello, B.; López-Aparicio, J.; Pérez-Calixto, D.; Cano-Jorge, M.; Vázquez-Victorio, G. Progress on the Use of Commercial Digital Optical Disc Units for Low-Power Laser Micromachining in Biomedical Applications. Micromachines 2018, 9, 187.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Micromachines EISSN 2072-666X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top