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Micromachines 2017, 8(4), 132; doi:10.3390/mi8040132

Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings

1
College of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan
2
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung 20401, Taiwan
3
Department of Mechanical and Mechatronic Engineering, National Taiwan Ocean University, Keelung 20224, Taiwan
4
Center for Marine Mechatronic Systems (CMMS), National Taiwan Ocean University, Keelung 20224, Taiwan
5
Division of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Keelung 20401, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editor: Jeng-Haur Horng
Received: 4 February 2017 / Revised: 31 March 2017 / Accepted: 16 April 2017 / Published: 19 April 2017
(This article belongs to the Special Issue Microtribology, Adhesion and Surface Engineering)
View Full-Text   |   Download PDF [10842 KB, uploaded 19 April 2017]   |  

Abstract

Biomedical coatings are used to promote the wear resistance and the biocompatibility of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the coatings by the amount material eroded by the surrounding fluid. However, there is still a lack of understanding with regards to the shaker’s rotating conditions and the corresponding physiological condition. This study implemented numerical simulations by establishing a fluid dynamic model to evaluate the intensity of the shear stress under various rotating speeds and diameters of the shaker. The results are valuable to conduct in vitro tests for estimating the performance of biomedical coatings under real hemodynamic conditions and can be applied to other fluid-contact implants. View Full-Text
Keywords: mechanical heart valve; computational fluid dynamics; degradation; biomedical coatings mechanical heart valve; computational fluid dynamics; degradation; biomedical coatings
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MDPI and ACS Style

Cherng, W.-J.; Dong, Z.-S.; Chou, C.-C.; Yeh, C.-H.; Pan, Y.-H. Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings. Micromachines 2017, 8, 132.

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