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Micromachines 2016, 7(5), 82; doi:10.3390/mi7050082

Three-Dimensional Fabrication for Microfluidics by Conventional Techniques and Equipment Used in Mass Production

Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
ImPACT Research Center for Advanced Nanobiodevices, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
Author to whom correspondence should be addressed.
Academic Editors: Manabu Tokeshi and Kiichi Sato
Received: 18 March 2016 / Revised: 26 April 2016 / Accepted: 27 April 2016 / Published: 4 May 2016
(This article belongs to the Special Issue Micro/Nano Devices for Chemical Analysis)
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This paper presents a simple three-dimensional (3D) fabrication method based on soft lithography techniques and laminated object manufacturing. The method can create 3D structures that have undercuts with general machines for mass production and laboratory scale prototyping. The minimum layer thickness of the method is at least 4 µm and bonding strength between layers is over 330 kPa. The performance reaches conventional fabrication techniques used for two-dimensionally (2D)-designed microfluidic devices. We fabricated some 3D structures, i.e., fractal structures, spiral structures, and a channel-in-channel structure, in microfluidic channels and demonstrated 3D microfluidics. The fabrication method can be achieved with a simple black light for bio-molecule detection; thus, it is useful for not only lab-scale rapid prototyping, but also for commercial manufacturing. View Full-Text
Keywords: 3D microfluidics; microfabrication 3D microfluidics; microfabrication

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Naito, T.; Nakamura, M.; Kaji, N.; Kubo, T.; Baba, Y.; Otsuka, K. Three-Dimensional Fabrication for Microfluidics by Conventional Techniques and Equipment Used in Mass Production. Micromachines 2016, 7, 82.

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