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Micromachines 2015, 6(4), 437-451; doi:10.3390/mi6040437

3D Printed Unibody Lab-on-a-Chip: Features Survey and Check-Valves Integration

Optical Devices Laboratory, Department of Physics, Chemistry and Biology, Linköping University, S58183 Linköping, Sweden
This paper is an extended version of our paper published in the 2nd International Conference on Microfluidic Handling Systems, Freiburg, Germany, 8–10 October 2014.
These authors contributed equally to this work.
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Author to whom correspondence should be addressed.
Academic Editor: Gerald A. Urban
Received: 6 February 2015 / Revised: 31 March 2015 / Accepted: 2 April 2015 / Published: 7 April 2015
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Abstract

The unibody lab-on-a-chip (ULOC) concept entails a fast and affordable micro-prototyping system built around a single monolithic 3D printed element (unibody). A consumer-grade stereo lithography (SL) 3D printer can configure ULOCs with different forms of sample delivery, transport, handling and readout, while minimizing material costs and fabrication time. ULOC centralizes all complex fabrication procedures and replaces the need for clean room resources, delivering prototypes for less than 1 US$, which can be printed in 10 min and ready for testing in less than 30 min. Recent examples of ULOC integration of transport, chemical sensing for optical readout and flow mixing capabilities are discussed, as well as the integration of the first check-valves for ULOC devices. ULOC valves are strictly unidirectional up to 100 psi, show an exponential forward flow behavior up to 70 psi and can be entirely fabricated with the ULOC approach. View Full-Text
Keywords: 3D printer; lab-on-a-chip; fast prototyping; unibody; micromixers; chemical sensing; check-valves; lateral flow; paper fluidics; integrated connectors; viability 3D printer; lab-on-a-chip; fast prototyping; unibody; micromixers; chemical sensing; check-valves; lateral flow; paper fluidics; integrated connectors; viability
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Comina, G.; Suska, A.; Filippini, D. 3D Printed Unibody Lab-on-a-Chip: Features Survey and Check-Valves Integration. Micromachines 2015, 6, 437-451.

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