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Micromachines 2015, 6(11), 1768-1793; doi:10.3390/mi6111455

Droplet Manipulations in Two Phase Flow Microfluidics

Physics of Complex Fluids Group, MESA+ Institute, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands
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Academic Editors: Andrew deMello and Xavier Casadevall i Solvas
Received: 25 September 2015 / Revised: 3 November 2015 / Accepted: 6 November 2015 / Published: 13 November 2015
(This article belongs to the Special Issue Droplet Microfluidics: Techniques and Technologies)
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Abstract

Even though droplet microfluidics has been developed since the early 1980s, the number of applications that have resulted in commercial products is still relatively small. This is partly due to an ongoing maturation and integration of existing methods, but possibly also because of the emergence of new techniques, whose potential has not been fully realized. This review summarizes the currently existing techniques for manipulating droplets in two-phase flow microfluidics. Specifically, very recent developments like the use of acoustic waves, magnetic fields, surface energy wells, and electrostatic traps and rails are discussed. The physical principles are explained, and (potential) advantages and drawbacks of different methods in the sense of versatility, flexibility, tunability and durability are discussed, where possible, per technique and per droplet operation: generation, transport, sorting, coalescence and splitting. View Full-Text
Keywords: droplet; two-phase-flow; manipulation; microfluidics; lab-on-a-chip droplet; two-phase-flow; manipulation; microfluidics; lab-on-a-chip
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Pit, A.M.; Duits, M.H.G.; Mugele, F. Droplet Manipulations in Two Phase Flow Microfluidics. Micromachines 2015, 6, 1768-1793.

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