Miscible Organic Solvents Soak Bonding Method Use in a PMMA Multilayer Microfluidic Device
AbstractIn this paper, we proposed a novel bonding technology to fabricate a microfluidic device based on Poly(methyl methacrylate) (PMMA). The method, which used chloroform and ethanol as miscible bonding solvent, can complete complex structures rapid assembly (10 min) at 40°C. A bonding strength of 267.5 N/cm2 can be achieved, while the micro channel deformation was less than 7.26%. Then we utilized this method to produce a three layers micro mixer, which included a T-shaped inlet channel and six H-shaped mixing units. Numerical simulation indicated that, the well mixing length of the mixer was only about 6 mm when Re = 10. Finally, fluorescence microscopy was used to verify mixer performance. The method provided the potential for mass production of multilayer rigid polymer microfluidic devices. View Full-Text
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Zhang, H.; Liu, X.; Li, T.; Han, X. Miscible Organic Solvents Soak Bonding Method Use in a PMMA Multilayer Microfluidic Device. Micromachines 2014, 5, 1416-1428.
Zhang H, Liu X, Li T, Han X. Miscible Organic Solvents Soak Bonding Method Use in a PMMA Multilayer Microfluidic Device. Micromachines. 2014; 5(4):1416-1428.Chicago/Turabian Style
Zhang, He; Liu, Xiaowei; Li, Tian; Han, Xiaowei. 2014. "Miscible Organic Solvents Soak Bonding Method Use in a PMMA Multilayer Microfluidic Device." Micromachines 5, no. 4: 1416-1428.