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Micromachines 2014, 5(4), 1416-1428; doi:10.3390/mi5041416

Miscible Organic Solvents Soak Bonding Method Use in a PMMA Multilayer Microfluidic Device

Key Laboratory of Micro-Systems and Micro-Structures Manufacturing, Harbin Institute of Technology, Harbin 150001, China
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Received: 23 September 2014 / Revised: 5 December 2014 / Accepted: 5 December 2014 / Published: 10 December 2014
(This article belongs to the Special Issue Micro/Nano Fabrication)
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Abstract

In this paper, we proposed a novel bonding technology to fabricate a microfluidic device based on Poly(methyl methacrylate) (PMMA). The method, which used chloroform and ethanol as miscible bonding solvent, can complete complex structures rapid assembly (10 min) at 40°C. A bonding strength of 267.5 N/cm2 can be achieved, while the micro channel deformation was less than 7.26%. Then we utilized this method to produce a three layers micro mixer, which included a T-shaped inlet channel and six H-shaped mixing units. Numerical simulation indicated that, the well mixing length of the mixer was only about 6 mm when Re = 10. Finally, fluorescence microscopy was used to verify mixer performance. The method provided the potential for mass production of multilayer rigid polymer microfluidic devices. View Full-Text
Keywords: PMMA; miscible organic solvents soak bonding; multilayer micro device; mixing efficiency PMMA; miscible organic solvents soak bonding; multilayer micro device; mixing efficiency
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Zhang, H.; Liu, X.; Li, T.; Han, X. Miscible Organic Solvents Soak Bonding Method Use in a PMMA Multilayer Microfluidic Device. Micromachines 2014, 5, 1416-1428.

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