Table of Contents
Toxins, Volume 9, Issue 5 (May 2017)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story Venom from the African tarantula Monocentropus balfouri was found to contain two insecticidal [...] Read more. Venom from the African tarantula Monocentropus balfouri was found to contain two insecticidal peptides (Mb1a and Mb1b) that paralyse houseflies and blowflies but not cotton bollworms. Both peptides inhibit voltage-gated sodium and calcium channels in neurons isolated from the American cockroach as well as the cloned BgNaV1 channel from the German cockroach. Mb1a also induces a delay in fast inactivation of BgNaV1. Comparison of the sodium channels of the tested insect species revealed that sequence variations in the S1–S2 extracellular loops of the voltage sensor domains might underlie the differences in activity between different phyla. The photo was taken by Bastian Rast. View this paper.