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Toxins 2016, 8(12), 361; doi:10.3390/toxins8120361

Recent Advances and Future Challenges in Modified Mycotoxin Analysis: Why HRMS Has Become a Key Instrument in Food Contaminant Research

1
Department of Food Science, University of Parma, Parco Area delle Scienze 95/A, Parma 43124, Italy
2
Center of Biomedicine, European Academy of Bolzano/Bozen, Via Galvani 31, Bolzano 39100, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Aldo Laganà
Received: 30 October 2016 / Revised: 23 November 2016 / Accepted: 25 November 2016 / Published: 2 December 2016
(This article belongs to the Special Issue LC-MS/MS Method for Mycotoxin Analysis)
View Full-Text   |   Download PDF [2211 KB, uploaded 2 December 2016]   |  

Abstract

Mycotoxins are secondary metabolites produced by pathogenic fungi in crops worldwide. These compounds can undergo modification in plants, leading to the formation of a large number of possible modified forms, whose toxicological relevance and occurrence in food and feed is still largely unexplored. The analysis of modified mycotoxins by liquid chromatography–mass spectrometry remains a challenge because of their chemical diversity, the large number of isomeric forms, and the lack of analytical standards. Here, the potential benefits of high-resolution and ion mobility mass spectrometry as a tool for separation and structure confirmation of modified mycotoxins have been investigated/reviewed. View Full-Text
Keywords: modified mycotoxins; high resolution mass spectrometry; ion mobility spectrometry modified mycotoxins; high resolution mass spectrometry; ion mobility spectrometry
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Righetti, L.; Paglia, G.; Galaverna, G.; Dall’Asta, C. Recent Advances and Future Challenges in Modified Mycotoxin Analysis: Why HRMS Has Become a Key Instrument in Food Contaminant Research. Toxins 2016, 8, 361.

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