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Toxins 2015, 7(7), 2413-2421; doi:10.3390/toxins7072413

Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases

1
Department of Korean Medicine Obstetrics and Gynecology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Korea
2
Department of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Korea
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Lai Ren
Received: 15 May 2015 / Revised: 16 May 2015 / Accepted: 24 June 2015 / Published: 29 June 2015
View Full-Text   |   Download PDF [319 KB, uploaded 29 June 2015]

Abstract

Bee Venom (BV) has long been used in Korea to relieve pain symptoms and to treat inflammatory diseases, such as rheumatoid arthritis. The underlying mechanisms of the anti-inflammatory and analgesic actions of BV have been proved to some extent. Additionally, recent clinical and experimental studies have demonstrated that BV and BV-derived active components are applicable to a wide range of immunological and neurodegenerative diseases, including autoimmune diseases and Parkinson’s disease. These effects of BV are known to be mediated by modulating immune cells in the periphery, and glial cells and neurons in the central nervous system. This review will introduce the scientific evidence of the therapeutic effects of BV and its components on several immunological and neurological diseases, and describe their detailed mechanisms involved in regulating various immune responses and pathological changes in glia and neurons. View Full-Text
Keywords: Bee Venom; immunological diseases; neurological diseases Bee Venom; immunological diseases; neurological diseases
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Hwang, D.-S.; Kim, S.K.; Bae, H. Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases. Toxins 2015, 7, 2413-2421.

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