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Toxins 2015, 7(6), 2024-2050; doi:10.3390/toxins7062024

Analysis of Ergot Alkaloids

Fera Science Ltd., Sand Hutton, North Yorks YO41 1LZ, UK
Academic Editor: Christopher L. Schardl
Received: 26 February 2015 / Revised: 12 May 2015 / Accepted: 20 May 2015 / Published: 3 June 2015
(This article belongs to the Special Issue Ergot Alkaloids: Chemistry, Biology and Toxicology)
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Abstract

The principles and application of established and newer methods for the quantitative and semi-quantitative determination of ergot alkaloids in food, feed, plant materials and animal tissues are reviewed. The techniques of sampling, extraction, clean-up, detection, quantification and validation are described. The major procedures for ergot alkaloid analysis comprise liquid chromatography with tandem mass spectrometry (LC-MS/MS) and liquid chromatography with fluorescence detection (LC-FLD). Other methods based on immunoassays are under development and variations of these and minor techniques are available for specific purposes. View Full-Text
Keywords: ergot; LSD; ergotamine; lysergic acid; ergovaline; mycotoxins ergot; LSD; ergotamine; lysergic acid; ergovaline; mycotoxins
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Crews, C. Analysis of Ergot Alkaloids. Toxins 2015, 7, 2024-2050.

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