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Toxins 2010, 2(8), 2117-2131; doi:10.3390/toxins2082117
Review

Multiple Roles of Staphylococcus aureus Enterotoxins: Pathogenicity, Superantigenic Activity, and Correlation to Antibiotic Resistance

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Received: 3 July 2010; Accepted: 9 August 2010 / Published: 10 August 2010
(This article belongs to the Special Issue Enterotoxins)
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Abstract: Heat-stable enterotoxins are the most notable virulence factors associated with Staphylococcus aureus, a common pathogen associated with serious community and hospital acquired diseases. Staphylococcal enterotoxins (SEs) cause toxic shock-like syndromes and have been implicated in food poisoning. But SEs also act as superantigens that stimulate T-cell proliferation, and a high correlation between these activities has been detected. Most of the nosocomial S. aureus infections are caused by methicillin-resistant S. aureus (MRSA) strains, and those resistant to quinolones or multiresistant to other antibiotics are emerging, leaving a limited choice for their control. This review focuses on these diverse roles of SE, their possible correlations and the influence in disease progression and therapy.
Keywords: enterotoxins; Staphylococcus aureus; superantigens; MRSA; immune response enterotoxins; Staphylococcus aureus; superantigens; MRSA; immune response
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ortega, E.; Abriouel, H.; Lucas, R.; Gálvez, A. Multiple Roles of Staphylococcus aureus Enterotoxins: Pathogenicity, Superantigenic Activity, and Correlation to Antibiotic Resistance. Toxins 2010, 2, 2117-2131.

AMA Style

Ortega E, Abriouel H, Lucas R, Gálvez A. Multiple Roles of Staphylococcus aureus Enterotoxins: Pathogenicity, Superantigenic Activity, and Correlation to Antibiotic Resistance. Toxins. 2010; 2(8):2117-2131.

Chicago/Turabian Style

Ortega, Elena; Abriouel, Hikmate; Lucas, Rosario; Gálvez, Antonio. 2010. "Multiple Roles of Staphylococcus aureus Enterotoxins: Pathogenicity, Superantigenic Activity, and Correlation to Antibiotic Resistance." Toxins 2, no. 8: 2117-2131.



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