Proteases as Insecticidal Agents
AbstractProteases from a variety of sources (viruses, bacteria, fungi, plants, and insects) have toxicity towards insects. Some of these insecticidal proteases evolved as venom components, herbivore resistance factors, or microbial pathogenicity factors, while other proteases play roles in insect development or digestion, but exert an insecticidal effect when over-expressed from genetically engineered plants or microbial pathogens. Many of these proteases are cysteine proteases, although insect-toxic metalloproteases and serine proteases have also been examined. The sites of protease toxic activity range from the insect midgut to the hemocoel (body cavity) to the cuticle. This review discusses these insecticidal proteases along with their evaluation and use as potential pesticides.
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Harrison, R.L.; Bonning, B.C. Proteases as Insecticidal Agents. Toxins 2010, 2, 935-953.
Harrison RL, Bonning BC. Proteases as Insecticidal Agents. Toxins. 2010; 2(5):935-953.Chicago/Turabian Style
Harrison, Robert L.; Bonning, Bryony C. 2010. "Proteases as Insecticidal Agents." Toxins 2, no. 5: 935-953.