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Toxins 2018, 10(6), 224; https://doi.org/10.3390/toxins10060224

Botulinum Toxin for Central Neuropathic Pain

1
Department of Rehabilitation Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Korea
2
Department of Rehabilitation Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Wangsan-ro 180, Dongdaemoon-Gu, Seoul 02559, Korea
*
Author to whom correspondence should be addressed.
Received: 30 April 2018 / Revised: 26 May 2018 / Accepted: 28 May 2018 / Published: 1 June 2018
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Abstract

Botulinum toxin (BTX) is widely used to treat muscle spasticity by acting on motor neurons. Recently, studies of the effects of BTX on sensory nerves have been reported and several studies have been conducted to evaluate its effects on peripheral and central neuropathic pain. Central neuropathic pain includes spinal cord injury-related neuropathic pain, post-stroke shoulder pain, multiple sclerosis-related pain, and complex regional pain syndrome. This article reviews the mechanism of central neuropathic pain and assesses the effect of BTX on central neuropathic pain. View Full-Text
Keywords: botulinum toxin; BTX; central neuropathic pain; spinal cord injury; post-stroke shoulder pain; complex regional pain syndrome botulinum toxin; BTX; central neuropathic pain; spinal cord injury; post-stroke shoulder pain; complex regional pain syndrome
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Park, J.; Chung, M.E. Botulinum Toxin for Central Neuropathic Pain. Toxins 2018, 10, 224.

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