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Toxins 2009, 1(2), 100-112; doi:10.3390/toxins1020100
Article

Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008

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Received: 9 October 2009; in revised form: 18 November 2009 / Accepted: 23 November 2009 / Published: 24 November 2009
(This article belongs to the Special Issue Animal Venoms)
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Abstract: A retrospective case review study of viper envenomations collected by the Marseille’s Poison Centre between 1996 and 2008 was performed. Results: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions. Conclusion: Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity.
Keywords: asp viper; snake envenomation; antivenom; neurotoxins; Vipera genus asp viper; snake envenomation; antivenom; neurotoxins; Vipera genus
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

De Haro, L.; Glaizal, M.; Tichadou, L.; Blanc-Brisset, I.; Hayek-Lanthois, M. Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008. Toxins 2009, 1, 100-112.

AMA Style

De Haro L, Glaizal M, Tichadou L, Blanc-Brisset I, Hayek-Lanthois M. Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008. Toxins. 2009; 1(2):100-112.

Chicago/Turabian Style

De Haro, Luc; Glaizal, Mathieu; Tichadou, Lucia; Blanc-Brisset, Ingrid; Hayek-Lanthois, Maryvonne. 2009. "Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008." Toxins 1, no. 2: 100-112.


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