Abstract: A retrospective case review study of viper envenomations collected by the Marseille’s Poison Centre between 1996 and 2008 was performed. Results: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions. Conclusion: Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity.
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De Haro, L.; Glaizal, M.; Tichadou, L.; Blanc-Brisset, I.; Hayek-Lanthois, M. Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008. Toxins 2009, 1, 100-112.
De Haro L, Glaizal M, Tichadou L, Blanc-Brisset I, Hayek-Lanthois M. Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008. Toxins. 2009; 1(2):100-112.
De Haro, Luc; Glaizal, Mathieu; Tichadou, Lucia; Blanc-Brisset, Ingrid; Hayek-Lanthois, Maryvonne. 2009. "Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008." Toxins 1, no. 2: 100-112.