Next Article in Journal
Whole Grain Intake and Glycaemic Control in Healthy Subjects: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Previous Article in Journal
Dose-Dependent Prebiotic Effect of Lactulose in a Computer-Controlled In Vitro Model of the Human Large Intestine
Article Menu
Issue 7 (July) cover image

Export Article

Open AccessArticle
Nutrients 2017, 9(7), 771; doi:10.3390/nu9070771

Self-Reported Non-Celiac Wheat Sensitivity in High School Students: Demographic and Clinical Characteristics

1
Internal Medicine, Dipartimento di Biologia e Medicina Interna e Specialistica, University of Palermo, 90133 Palermo, Italy
2
Internal Medicine Department, Giovanni Paolo II Hospital, 92019 Sciacca, Italy
3
Department of Economics, Management and Statistics, University of Palermo, 90127 Palermo, Italy
4
Dipartimento di Biologia e Medicina Interna e Specialistica, Division of Internal Medicine, Policlinico University Hospital, 90127 Palermo, Italy
*
Author to whom correspondence should be addressed.
Received: 16 May 2017 / Revised: 3 July 2017 / Accepted: 10 July 2017 / Published: 19 July 2017
View Full-Text   |   Download PDF [1297 KB, uploaded 19 July 2017]   |  

Abstract

Background: Non-Celiac Wheat Sensitivity (NCWS) has recently been included among the gluten-related disorders. As no biomarkers of this disease exist, its frequency has been estimated based on self-reported symptoms, but to date no data are available about self-reported NCWS in teenagers. Aim: To explore the prevalence of self-reported NCWS in a group of high school students and to study their demographic and clinical characteristics. Methods: The study was performed between April 2015 and January 2016 in two high schools of a coastal town in the south of Sicily (Italy). A total of 555 students (mean age 17 years, 191 male, 364 female) completed a modified validated questionnaire for self-reported NCWS. The subjects who self-reported NCWS were then compared with all the others. Results: Seven individuals (1.26%) had an established diagnosis of CD. The prevalence of self-reported NCWS was 12.2%, and 2.9% were following a gluten-free diet (GFD). Only 15 out of 68 (23%) NCWS self-reporters had consulted a doctor for this problem and only nine (14%) had undergone serological tests for celiac disease. The NCWS self-reporters very often had IBS symptoms (44%). Conclusions: Self-reported NCWS was found to be common in teenagers, with a frequency of 12.2%; the frequency of GFD use was 2.9%, which was much higher than the percentage of known CD in the same population (1.26%). A greater awareness of the possible implications on the part of the subjects involved, and a more thorough medical approach to the study of self-reported wheat-induced symptoms are required. View Full-Text
Keywords: self-reported non-celiac wheat sensitivity; non-celiac gluten-sensitivity; epidemiology; prevalence; teenagers; IBS; food allergy self-reported non-celiac wheat sensitivity; non-celiac gluten-sensitivity; epidemiology; prevalence; teenagers; IBS; food allergy
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Carroccio, A.; Giambalvo, O.; Blasca, F.L.; Iacobucci, R.; D’Alcamo, A.; Mansueto, P. Self-Reported Non-Celiac Wheat Sensitivity in High School Students: Demographic and Clinical Characteristics. Nutrients 2017, 9, 771.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top