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Nutrients 2017, 9(7), 658; doi:10.3390/nu9070658

Clinical Identification of Geriatric Patients with Hypovitaminosis D: The ‘Vitamin D Status Predictor for Geriatrics’ Study

1
Department of Neurosciences and Aging, Division of Geriatric Medicine, Angers University Hospital, Angers University Memory Clinic, Research Center on Autonomy and Longevity, University of Angers, UPRES EA 4638, UNAM, 49035 Angers, France
2
Department of Medical Biophysics, Robarts Research Institute, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, ON N6A 3K7, Canada
3
INSERM, MINT, 1066, University of Angers, 49035 Angers, France
4
Delegation to Clinical Research and Innovation, Angers University Hospital, 49100 Angers, France
5
Health Faculty, School of Medicine, F-49045 Angers, France
6
Department of Sports Medicine and Vascular Investigations, Angers University Hospital, 49100 Angers, France
7
Université de Bordeaux, ISPED, Centre INSERM U1219-Bordeaux Population Health, 61292 Bordeaux, France
Current address: Department of Geriatrics, Angers University Hospital, F-49933 Angers CEDEX 9, France.
*
Author to whom correspondence should be addressed.
Received: 3 May 2017 / Revised: 19 June 2017 / Accepted: 20 June 2017 / Published: 27 June 2017
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Abstract

The 16-item Vitamin D Status Predictor (VDSP) tool identifies healthy older community-dwellers at risk of hypovitaminosis D and may guide the use of blood tests in this population. The objective of the present hospital-based study was to test the efficacy of the VDSP to identify geriatric patients with hypovitaminosis D. The study included 199 nonsupplemented geriatric in- and outpatients consecutively admitted to Angers University Hospital, France (mean ± SD, 82.0 ± 7.8 years; 53.3% female). Serum 25-hydroxyvitaminD (25(OH)D) was measured at the time of the physician-administered VDSP. Hypovitaminosis D was defined as serum 25(OH)D concentration ≤ 75 nmol/L for vitamin D insufficiency, 25(OH)D ≤ 50 nmol/L for vitamin D deficiency, and 25(OH)D ≤ 25 nmol/L for severe vitamin D deficiency. We found that 184 participants (92.4%) had vitamin D insufficiency, 136 (68.3%) had vitamin D deficiency, and 67 (33.7%) had severe vitamin D deficiency. The VDSP identified severe vitamin D deficiency with an area under curve (AUC) = 0.83 and OR = 24.0. The VDSP was able to identify vitamin D deficiency and vitamin D insufficiency with less accuracy (AUC = 0.71 and AUC = 0.73, respectively). In conclusion, the 16-item VDSP is a short questionnaire that accurately identifies geriatric patients with severe vitamin D deficiency. This tool may guide the use of blood collection for determining geriatric patients’ vitamin D status. View Full-Text
Keywords: screening; vitamin D; vitamin D deficiency; older adults; hospital related screening; vitamin D; vitamin D deficiency; older adults; hospital related
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MDPI and ACS Style

Annweiler, C.; Riou, J.; Alessandri, A.; Gicquel, D.; Henni, S.; Féart, C.; Kabeshova, A. Clinical Identification of Geriatric Patients with Hypovitaminosis D: The ‘Vitamin D Status Predictor for Geriatrics’ Study. Nutrients 2017, 9, 658.

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