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Nutrients 2017, 9(6), 609; doi:10.3390/nu9060609

Protein Hydrolysates as Promoters of Non-Haem Iron Absorption

1
College of Life Sciences, China Jiliang University, Hangzhou 310018, China
2
Key Lab of Marine Food Quality and Hazard Controlling Technology of Zhejiang Province, Hangzhou 310018, China
3
National and Local United Engineering Lab of Quality Controlling Technology and Instrument for Marine Food, Hangzhou 310018, China
*
Author to whom correspondence should be addressed.
Received: 24 March 2017 / Revised: 13 May 2017 / Accepted: 13 June 2017 / Published: 15 June 2017
(This article belongs to the Special Issue Dietary Supplements)
View Full-Text   |   Download PDF [652 KB, uploaded 15 June 2017]   |  

Abstract

Iron (Fe) is an essential micronutrient for human growth and health. Organic iron is an excellent iron supplement due to its bioavailability. Both amino acids and peptides improve iron bioavailability and absorption and are therefore valuable components of iron supplements. This review focuses on protein hydrolysates as potential promoters of iron absorption. The ability of protein hydrolysates to chelate iron is thought to be a key attribute for the promotion of iron absorption. Iron-chelatable protein hydrolysates are categorized by their absorption forms: amino acids, di- and tri-peptides and polypeptides. Their structural characteristics, including their size and amino acid sequence, as well as the presence of special amino acids, influence their iron chelation abilities and bioavailabilities. Protein hydrolysates promote iron absorption by keeping iron soluble, reducing ferric iron to ferrous iron, and promoting transport across cell membranes into the gut. We also discuss the use and relative merits of protein hydrolysates as iron supplements. View Full-Text
Keywords: amino acid; di-peptide; tri-peptide; polypeptide; iron chelate; food supplement; bioactive peptides amino acid; di-peptide; tri-peptide; polypeptide; iron chelate; food supplement; bioactive peptides
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Li, Y.; Jiang, H.; Huang, G. Protein Hydrolysates as Promoters of Non-Haem Iron Absorption. Nutrients 2017, 9, 609.

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