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Nutrients 2017, 9(10), 1126; doi:10.3390/nu9101126

Nutritional Therapy in Liver Transplantation

1
Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
2
Department of General Surgery, Mansoura University, Mansoura 35516, Egypt
3
L’AORN Children’s Hospital Santobono and Pausilipon, Napoli 80122, Italy
*
Author to whom correspondence should be addressed.
Received: 23 August 2017 / Revised: 10 October 2017 / Accepted: 12 October 2017 / Published: 16 October 2017
(This article belongs to the Special Issue Nutrition and Liver Disease)
View Full-Text   |   Download PDF [1510 KB, uploaded 16 October 2017]   |  

Abstract

Protein-energy malnourishment is commonly encountered in patients with end-stage liver disease who undergo liver transplantation. Malnutrition may further increase morbidity, mortality and costs in the post-transplantation setting. The importance of carefully assessing the nutritional status during the work-up of patients who are candidates for liver replacement is widely recognized. The metabolic abnormalities induced by liver failure render the conventional assessment of nutritional status to be challenging. Preoperative loss of skeletal muscle mass, namely, sarcopenia, has a significant detrimental impact on post-transplant outcomes. It is essential to provide sufficient nutritional support during all phases of liver transplantation. Oral nutrition is preferred, but tube enteral nutrition may be required to provide the needed energy intake. Herein, the latest currently employed perioperative nutritional interventions in liver transplant recipients are thoroughly illustrated including synbiotics, micronutrients, branched-chain amino acid supplementation, immunonutrition formulas, fluid and electrolyte balance, the offering of nocturnal meals, dietary counselling, exercise and rehabilitation. View Full-Text
Keywords: liver transplantation; immunonutrition; synbiotics; nutritional intervention; sarcopenia; branched-chain amino acids; nutraceuticals liver transplantation; immunonutrition; synbiotics; nutritional intervention; sarcopenia; branched-chain amino acids; nutraceuticals
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Hammad, A.; Kaido, T.; Aliyev, V.; Mandato, C.; Uemoto, S. Nutritional Therapy in Liver Transplantation. Nutrients 2017, 9, 1126.

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