Animal Models of Nonalcoholic Fatty Liver Disease—A Starter’s Guide
AbstractNonalcoholic fatty liver disease (NAFLD) constitutes a major health concern with the increasing incidence of obesity and diabetes in many Western countries, reaching a prevalence of up to 30% in the general population. Animal models have played a vital role in elucidating the pathophysiological mechanisms of NAFLD and continue to do so. A myriad of different models exists, each with its advantages and disadvantages. This review presents a brief overview of these models with a particular focus on the basic mechanisms and physical, biochemical and histological phenotype. Both nutritional and chemically induced, as well as genetic models are examined, including models combining different approaches. View Full-Text
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Van Herck, M.A.; Vonghia, L.; Francque, S.M. Animal Models of Nonalcoholic Fatty Liver Disease—A Starter’s Guide. Nutrients 2017, 9, 1072.
Van Herck MA, Vonghia L, Francque SM. Animal Models of Nonalcoholic Fatty Liver Disease—A Starter’s Guide. Nutrients. 2017; 9(10):1072.Chicago/Turabian Style
Van Herck, Mikhaïl A.; Vonghia, Luisa; Francque, Sven M. 2017. "Animal Models of Nonalcoholic Fatty Liver Disease—A Starter’s Guide." Nutrients 9, no. 10: 1072.
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