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Nutrients 2016, 8(11), 713; doi:10.3390/nu8110713

Nutraceuticals and Their Potential to Treat Duchenne Muscular Dystrophy: Separating the Credible from the Conjecture

1
Murdoch Childrens Research Institute, Royal Children’s Hospital, Parkville 3052, Australia
2
Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville 3010, Australia
3
Department of Pediatrics, The University of Melbourne, Parkville 3010, Australia
*
Author to whom correspondence should be addressed.
Received: 29 August 2016 / Revised: 20 October 2016 / Accepted: 4 November 2016 / Published: 9 November 2016
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Abstract

In recent years, complementary and alternative medicine has become increasingly popular. This trend has not escaped the Duchenne Muscular Dystrophy community with one study showing that 80% of caregivers have provided their Duchenne patients with complementary and alternative medicine in conjunction with their traditional treatments. These statistics are concerning given that many supplements are taken based on purely “anecdotal” evidence. Many nutraceuticals are thought to have anti-inflammatory or anti-oxidant effects. Given that dystrophic pathology is exacerbated by inflammation and oxidative stress these nutraceuticals could have some therapeutic benefit for Duchenne Muscular Dystrophy (DMD). This review gathers and evaluates the peer-reviewed scientific studies that have used nutraceuticals in clinical or pre-clinical trials for DMD and thus separates the credible from the conjecture. View Full-Text
Keywords: Duchenne muscular dystrophy; Becker muscular dystrophy; muscle; nutraceuticals; mdx Duchenne muscular dystrophy; Becker muscular dystrophy; muscle; nutraceuticals; mdx
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Woodman, K.G.; Coles, C.A.; Lamandé, S.R.; White, J.D. Nutraceuticals and Their Potential to Treat Duchenne Muscular Dystrophy: Separating the Credible from the Conjecture. Nutrients 2016, 8, 713.

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