Next Article in Journal
DHA Effects in Brain Development and Function
Next Article in Special Issue
Dietary Selenium and Human Health
Previous Article in Journal
Effect of Glycemic Index of Breakfast on Energy Intake at Subsequent Meal among Healthy People: A Meta-Analysis
Previous Article in Special Issue
Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice
Article Menu

Export Article

Open AccessArticle
Nutrients 2016, 8(1), 24; doi:10.3390/nu8010024

Significant Beneficial Association of High Dietary Selenium Intake with Reduced Body Fat in the CODING Study

1
Department of Endocrinology, the First Affiliated Hospital of Dalian Medical University, Dalian 116000, Liaoning, China
2
The Discipline of Medicine, Faculty of Medicine, Memorial University, St. John’s, NL A1B 3V6, Canada
3
College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China
4
Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada
5
Division of Community Health & Humanities, Faculty of Medicine, Memorial University, St. John’s, NL A1B 3V6, Canada
*
Author to whom correspondence should be addressed.
Received: 22 October 2015 / Revised: 21 December 2015 / Accepted: 22 December 2015 / Published: 4 January 2016
(This article belongs to the Special Issue Dietary Selenium and Human Health)
View Full-Text   |   Download PDF [410 KB, uploaded 4 January 2016]   |  

Abstract

Selenium (Se) is a trace element which plays an important role in adipocyte hypertrophy and adipogenesis. Some studies suggest that variations in serum Se may be associated with obesity. However, there are few studies examining the relationship between dietary Se and obesity, and findings are inconsistent. We aimed to investigate the association between dietary Se intake and a panel of obesity measurements with systematic control of major confounding factors. A total of 3214 subjects participated in the study. Dietary Se intake was determined from the Willett food frequency questionnaire. Body composition was measured using dual-energy X-ray absorptiometry. Obese men and women had the lowest dietary Se intake, being 24% to 31% lower than corresponding normal weight men and women, classified by both BMI and body fat percentage. Moreover, subjects with the highest dietary Se intake had the lowest BMI, waist circumference, and trunk, android, gynoid and total body fat percentages, with a clear dose-dependent inverse relationship observed in both gender groups. Furthermore, significant negative associations discovered between dietary Se intake and obesity measurements were independent of age, total dietary calorie intake, physical activity, smoking, alcohol, medication, and menopausal status. Dietary Se intake alone may account for 9%–27% of the observed variations in body fat percentage. The findings from this study strongly suggest that high dietary Se intake is associated with a beneficial body composition profile. View Full-Text
Keywords: dietary selenium intake; body composition; confounding factors; adult population dietary selenium intake; body composition; confounding factors; adult population
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Wang, Y.; Gao, X.; Pedram, P.; Shahidi, M.; Du, J.; Yi, Y.; Gulliver, W.; Zhang, H.; Sun, G. Significant Beneficial Association of High Dietary Selenium Intake with Reduced Body Fat in the CODING Study. Nutrients 2016, 8, 24.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top