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Nutrients 2015, 7(12), 10369-10387; doi:10.3390/nu7125536

The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

1
Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China
2
Department of Endocrinology and Metabolism, The Third People’s Hospital of Chengdu, Chengdu 610031, China
3
Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China
4
Department of Clinical Nutrition, West China Hospital, Sichuan University, Chengdu 610041, China
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 29 September 2015 / Revised: 11 November 2015 / Accepted: 26 November 2015 / Published: 10 December 2015
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Abstract

The present study aimed to comprehensively assess if oats intake is beneficial for diabetic patients. The literature search was conducted in PubMed database up to 23 August 2015. Fourteen controlled trials and two uncontrolled observational studies were included. Compared with the controls, oats intake significantly reduced the concentrations of glycosylated hemoglobin A1c (HbA1c) (MD, −0.42%; 95% CI, −0.61% to −0.23%), fasting blood glucose (FBG) (MD, −0.39 mmol/L; 95% CI, −0.58 to −0.19 mmol/L), total cholesterol (TC) (MD, −0.49 mmol/L; 95% CI, −0.86 to −0.12 mmol/L), low-density lipoprotein cholesterol (LDL-C) (MD, −0.29 mmol/L; 95% CI, −0.48 to −0.09 mmol/L). Oatmeal significantly reduced the acute postprandial glucose and insulin responses compared with the control meal. The present study has revealed a beneficial effect of oats intake on glucose control and lipid profiles in type 2 diabetic patients. Further investigations of oats intake in patients with type 1 diabetes and the safety of oats consumption are required. View Full-Text
Keywords: oats; β-glucan; type 2 diabetes mellitus; glycemic control; cholesterol; systematic review; meta-analysis oats; β-glucan; type 2 diabetes mellitus; glycemic control; cholesterol; systematic review; meta-analysis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Hou, Q.; Li, Y.; Li, L.; Cheng, G.; Sun, X.; Li, S.; Tian, H. The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. Nutrients 2015, 7, 10369-10387.

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