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Nutrients 2015, 7(1), 196-208; doi:10.3390/nu7010196

Heart Rate Variability and Cognitive Function Following a Multi-Vitamin and Mineral Supplementation with Added Guarana (Paullinia cupana)

Laboratory of Human Motricity, Education, Sport and Health (EA 6309), University of Nice Sophia Antipolis, Nice 06205, France
Aix Marseille University, CNRS, LPC UMR 7290, FR 3C FR 3512, Marseille 13000, France
National Institute for Sport Expertise and Performance, Paris 75012, France
Creps Sud-Est, Aix en Provence 13080, France
Author to whom correspondence should be addressed.
Received: 31 October 2014 / Accepted: 16 December 2014 / Published: 31 December 2014
View Full-Text   |   Download PDF [155 KB, uploaded 31 December 2014]   |  


The aim of this study was to assess cognitive performance and heart rate variability (HRV) following the ingestion of either a multi-vitamin-mineral preparation supplemented with 300 mg guarana (Ac); a caffeine supplement (C) or a placebo supplement (Pl). Fifty-six subjects took part in a randomized, double-blind crossover design, consisting of three experimental sessions ran on a different day. Cognitive performance was assessed using a go/no-go task and a simple reaction time (SRT) task. HRV was assessed in the time domain (RMSSD) and in the frequency domain (HF) and cognitive tasks were performed before ingestion, 15 min after ingestion and then every 15 min over the course of 3 h. Responses were faster (without change in accuracy) when the go/no-go task was performed between 30 and 90 min after ingestion of Ac (4.6% ± 0.8%, p < 0.05). No effect was observed on SRT task. A significant decrease in HRV was observed during the first hour under C and Pl, whereas HRV remained stable under Ac. The results suggest that the ingestion of a multi-vitamin-mineral with added guarana improves decision-making performance and is accompanied by a stable autonomic nervous system regulation during the first hour. View Full-Text
Keywords: guarana; reaction time; decision-making; caffeine; heart rate variability guarana; reaction time; decision-making; caffeine; heart rate variability

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Pomportes, L.; Davranche, K.; Brisswalter, I.; Hays, A.; Brisswalter, J. Heart Rate Variability and Cognitive Function Following a Multi-Vitamin and Mineral Supplementation with Added Guarana (Paullinia cupana). Nutrients 2015, 7, 196-208.

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