Next Article in Journal
Exercise-Trained Men and Women: Role of Exercise and Diet on Appetite and Energy Intake
Next Article in Special Issue
Vitamin D Status and Related Factors in Newborns in Shanghai, China
Previous Article in Journal
Biochemical Validation of the Older Australian’s Food Frequency Questionnaire Using Carotenoids and Vitamin E
Previous Article in Special Issue
Dietary and Health Profiles of Spanish Women in Preconception, Pregnancy and Lactation
Article Menu

Export Article

Open AccessArticle
Nutrients 2014, 6(11), 4918-4934; doi:10.3390/nu6114918

Polyunsaturated Fatty Acid Composition of Maternal Diet and Erythrocyte Phospholipid Status in Chilean Pregnant Women

Department of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile
Obstetrics and Gynecology Department, Clinical Hospital of the University of Chile, Av. Santos Dumont 999, Independencia, Santiago 8380453, Chile
Lipid Center, Institute of Nutrition and Food Technology (INTA), University of Chile, Av. El Líbano 5524, Macul, Santiago 8380453, Chile
Author to whom correspondence should be addressed.
Received: 11 September 2014 / Revised: 14 October 2014 / Accepted: 24 October 2014 / Published: 7 November 2014
(This article belongs to the Special Issue Nutrition in Pregnancy)
View Full-Text   |   Download PDF [504 KB, uploaded 7 November 2014]   |  


Chilean diets are characterized by a low supply of n-3 polyunsaturated fatty acids (n-3 PUFA), which are critical nutrients during pregnancy and lactation, because of their role in brain and visual development. DHA is the most relevant n-3 PUFA in this period. We evaluated the dietary n-3 PUFA intake and erythrocyte phospholipids n-3 PUFA in Chilean pregnant women. Eighty healthy pregnant women (20–36 years old) in the 3rd–6th month of pregnancy were included in the study. Dietary assessment was done applying a food frequency questionnaire, and data were analyzed through the Food Processor SQL® software. Fatty acids of erythrocyte phospholipids were assessed by gas-liquid chromatography. Diet composition was high in saturated fat, low in mono- and PUFA, high in n-6 PUFA (linoleic acid) and low in n-3 PUFA (alpha-linolenic acid and DHA), with imbalance in the n-6/n-3 PUFA ratio. Similar results were observed for fatty acids from erythrocyte phospholipids. The sample of Chilean pregnant women showed high consumption of saturated fat and low consumption of n-3 PUFA, which is reflected in the low DHA content of erythrocyte phospholipids. Imbalance between n-6/n-3 PUFA could negatively affect fetal development. New strategies are necessary to improve n-3 PUFA intake throughout pregnancy and breast feeding periods. Furthermore, it is necessary to develop dietary interventions to improve the quality of consumed foods with particular emphasis on n-3 PUFA. View Full-Text
Keywords: pregnancy; dietary intake; n-6 and n-3 PUFA intake; DHA; fatty acid phospholipids pregnancy; dietary intake; n-6 and n-3 PUFA intake; DHA; fatty acid phospholipids

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Bascuñán, K.A.; Valenzuela, R.; Chamorro, R.; Valencia, A.; Barrera, C.; Puigrredon, C.; Sandoval, J.; Valenzuela, A. Polyunsaturated Fatty Acid Composition of Maternal Diet and Erythrocyte Phospholipid Status in Chilean Pregnant Women. Nutrients 2014, 6, 4918-4934.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top