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Nutrients 2014, 6(10), 4610-4624; doi:10.3390/nu6104610

Comparative Study on the Hypoglycemic and Antioxidative Effects of Fermented Paste (Doenjang) Prepared from Soybean and Brown Rice Mixed with Rice Bran or Red Ginseng Marc in Mice Fed with High Fat Diet

Department of Food Science and Nutrition, Brain Korea 21 Plus, Kyungpook National Universiy, 1370 Sankyuk-ong, Degu 702-701, Korea
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Received: 23 June 2014 / Revised: 29 September 2014 / Accepted: 9 October 2014 / Published: 22 October 2014
(This article belongs to the Special Issue Nutrient Fortification and Human Health)
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Abstract

The effects of fermented paste made from soybean, brown rice, or brown rice in combination with rice bran or red ginseng marc on the glucose metabolism and antioxidative defense system in high fat-fed mice were investigated. The mice were given experimental diets for eight weeks: Normal control, high fat, and high fat supplemented with soybean fermented paste, brown rice fermented paste, brown rice-rice bran fermented paste, or brown rice-red ginseng marc fermented paste. The high fat group showed markedly higher blood glucose level and erythrocyte lipid peroxidation than the normal control group. Diet supplementation of fermented paste inhibited the high fat-induced hyperglycemia and oxidative stress via regulation of the glucose-regulating and antioxidant enzymes activities. The soybean and brown rice-red ginseng marc fermented pastes were the most effective in improving the glucose metabolism and antioxidant defense status in mice under high fat diet condition. These findings illustrate that brown rice, in combination with red ginseng marc, may be useful in the development of fermented paste with strong hypoglycemic and antioxidative activities. View Full-Text
Keywords: antioxidative effect; brown rice; fermented paste; hypoglycemic effect; soybean antioxidative effect; brown rice; fermented paste; hypoglycemic effect; soybean
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Chung, S.I.; Rico, C.W.; Kang, M.Y. Comparative Study on the Hypoglycemic and Antioxidative Effects of Fermented Paste (Doenjang) Prepared from Soybean and Brown Rice Mixed with Rice Bran or Red Ginseng Marc in Mice Fed with High Fat Diet. Nutrients 2014, 6, 4610-4624.

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