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Nutrients 2010, 2(3), 389-407; doi:10.3390/nu2030389
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Vitamin D status during Pregnancy and Aspects of Offspring Health

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Received: 18 January 2010 / Revised: 15 March 2010 / Accepted: 17 March 2010 / Published: 23 March 2010
(This article belongs to the Special Issue Feature Papers for Vitamins)
View Full-Text   |   Download PDF [197 KB, 24 March 2010; original version 23 March 2010]   |   Browse Figure

Abstract

Low maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known.
Keywords: vitamin D; ultraviolet radiation; sun exposure; pregnancy; offspring health vitamin D; ultraviolet radiation; sun exposure; pregnancy; offspring health
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ponsonby, A.-L.; Lucas, R.M.; Lewis, S.; Halliday, J. Vitamin D status during Pregnancy and Aspects of Offspring Health. Nutrients 2010, 2, 389-407.

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