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Nutrients 2010, 2(3), 389-407; doi:10.3390/nu2030389

Vitamin D status during Pregnancy and Aspects of Offspring Health

1
Murdoch Childrens Research Institute, Royal Children’s Hospital, Parkville, Melbourne, 3052 Australia
2
National Centre for Epidemiology and Population Health, The Australian National University, Canberra, 0200 Australia
3
Department of Paediatrics, University of Melbourne, Royal Children’s Hospital, Parkville, Melbourne, 3052 Australia
*
Author to whom correspondence should be addressed.
Received: 18 January 2010 / Revised: 15 March 2010 / Accepted: 17 March 2010 / Published: 23 March 2010
(This article belongs to the Special Issue Feature Papers for Vitamins)
View Full-Text   |   Download PDF [197 KB, 24 March 2010; original version 23 March 2010]   |  

Abstract

Low maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known. View Full-Text
Keywords: vitamin D; ultraviolet radiation; sun exposure; pregnancy; offspring health vitamin D; ultraviolet radiation; sun exposure; pregnancy; offspring health
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Ponsonby, A.-L.; Lucas, R.M.; Lewis, S.; Halliday, J. Vitamin D status during Pregnancy and Aspects of Offspring Health. Nutrients 2010, 2, 389-407.

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