Next Article in Journal
The Biological Activities of Oleocanthal from a Molecular Perspective
Previous Article in Journal
Association between Dietary Zinc Intake and Hyperuricemia among Adults in the United States
Article Menu
Issue 5 (May) cover image

Export Article

Open AccessArticle
Nutrients 2018, 10(5), 569; https://doi.org/10.3390/nu10050569

A Randomized, Placebo-Controlled Study on the Safety and Efficacy of Daily Ingestion of Green Tea (Camellia sinensis L.) cv. “Yabukita” and “Sunrouge” on Eyestrain and Blood Pressure in Healthy Adults

1
Agri-Food Business Innovation Center, National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki 305-8517, Japan
2
Department of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido 069-8585, Japan
3
Department of Ophthalmology, Health Sciences University of Hokkaido, Ishikari-gun, Hokkaido 002-8072, Japan
4
Institute of Fruit and Tea Science, NARO, Makurazaki, Kagoshima 898-0087, Japan
5
Institute of Fruit and Tea Science, NARO, Shimada, Shizuoka 428-8501, Japan
6
Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Fukuoka 812-8581, Japan
*
Author to whom correspondence should be addressed.
Received: 25 March 2018 / Revised: 30 April 2018 / Accepted: 3 May 2018 / Published: 6 May 2018
View Full-Text   |   Download PDF [1819 KB, uploaded 7 May 2018]   |  

Abstract

The green tea (Camellia sinensis L.) cultivar “Sunrouge” contains anthocyanins, catechins and flavonols. To determine whether ingesting green tea containing anthocyanins improves visual function and blood pressure (BP) in healthy adults, a randomized, double-blind, placebo-controlled study was performed. A total of 120 healthy subjects, aged between 20 and 60 years and with a systolic BP (SBP) value of ≤125 and <155 and a diastolic BP (DBP) value <95, or a DBP of ≤75 mmHg and <95 mmHg and a SBP <155 mmHg, were randomly assigned to one of three groups. For 12 weeks, the placebo group received barley extract without catechin; another group received “Sunrouge” extract containing 11.2 mg anthocyanin and 323.6 mg epigallocatechin-3-O-gallate (EGCG); and a third group received “Yabukita” extract containing 322.2 mg EGCG. Home BP, accommodation ability, visual analog scale questionnaires for eyestrain, and metabolic-associated markers were analyzed at weeks 0, 4, 8, and 12 of the intake period. The ingestion of “Sunrouge” tea significantly improved accommodation ability and eyestrain in subjects younger than 45 years and in subjects who operated visual display terminals every day. It also elevated BP. “Yabukita” tea ingestion significantly increased serum adiponectin levels. No adverse effects were observed. We conclude that long-term intake of “Sunrouge” tea containing anthocyanins and flavonols might improve visual function. View Full-Text
Keywords: green tea cv. “Sunrouge” or “Yabukita”; anthocyanins; flavonols; eyestrain reducing effect; blood pressure elevating effect; adiponectin level increasing effect green tea cv. “Sunrouge” or “Yabukita”; anthocyanins; flavonols; eyestrain reducing effect; blood pressure elevating effect; adiponectin level increasing effect
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Maeda-Yamamoto, M.; Nishimura, M.; Kitaichi, N.; Nesumi, A.; Monobe, M.; Nomura, S.; Horie, Y.; Tachibana, H.; Nishihira, J. A Randomized, Placebo-Controlled Study on the Safety and Efficacy of Daily Ingestion of Green Tea (Camellia sinensis L.) cv. “Yabukita” and “Sunrouge” on Eyestrain and Blood Pressure in Healthy Adults. Nutrients 2018, 10, 569.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top