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Sustainability 2016, 8(11), 1131; doi:10.3390/su8111131

Bioactivity of Phycocolloids against the Mediterranean Protozoan Leishmania infantum: An Inceptive Study

1
CNR-ISMAR, Institute of Marine Sciences, Arsenale 101-104, Castello 2737F, 30122 Venice, Italy
2
Department of Environmental Sciences, Informatics and Statistics, University Ca’ Foscari Venice, Dorsoduro 2137, 30123 Venice, Italy
3
Centro di Referenza Nazionale per le Leishmaniosi (C.Re.Na.L.), Istituto Zooprofilattico Sperimentale della Sicilia, Viale Gino Marinuzzi 3, 90129 Palermo, Italy
4
Department of Biological and Environmental Sciences (Botany), University of Messina, Salita Sperone 31, 98166 Messina, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Vincenzo Torretta
Received: 8 September 2016 / Revised: 23 October 2016 / Accepted: 27 October 2016 / Published: 4 November 2016
(This article belongs to the Section Sustainable Use of the Environment and Resources)
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Abstract

Sulfated polysaccharides from marine macroalgae have been shown to possess a variety of biological activities against fungi, bacteria, viruses, and protozoa. In this study, the in vitro activity of algal polysaccharides against Leishmania infantum (Kinetoplastida: Trypanosomatidae) was investigated. The polysaccharides were extracted from different macroalgae of the Mediterranean Sea: Chaetomorpha linum, Agardhiella subulata, Gracilaria viridis, Gracilaria bursa-pastoris, Hypnea cornuta, Sargassum muticum, and Undaria pinnatifida. Preliminary results showed a good anti-leishmanial activity of the investigated species, encouraging the focus on their use as natural resources in order to match integrated management strategies for the employment of local macroalgae. View Full-Text
Keywords: seaweeds; phycocolloids; Leishmania infantum seaweeds; phycocolloids; Leishmania infantum
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MDPI and ACS Style

Armeli Minicante, S.; Michelet, S.; Bruno, F.; Castelli, G.; Vitale, F.; Sfriso, A.; Morabito, M.; Genovese, G. Bioactivity of Phycocolloids against the Mediterranean Protozoan Leishmania infantum: An Inceptive Study. Sustainability 2016, 8, 1131.

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