Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals

doi:10.3390/pharmaceutics2010050

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Pharmaceutics 2010, 2(1), 50-60; doi:10.3390/pharmaceutics2010050

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Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals

Connie M. Remsberg , Renee L. Good and Neal M. Davies *

Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, Pullman, WA 99164-6534, USA

* Author to whom correspondence should be addressed.

Received: 28 January 2010; in revised form: 3 March 2010 / Accepted: 4 March 2010 / Published: 8 March 2010

(This article belongs to the Special Issue What\'s on Board in Pharmaceutics)

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Abstract: Label claims of vitamin E succinate and polyphenolic nutraceuticals are assessed. A validated HPLC method was utilized to assess vitamin E succinate products. Three novel LC/MS methods were used to assess the polyphenols, pterostilbene, phloretin, and myricetin, in dietary supplements. The amount of vitamin E succinate varied from 0-130% of the stated label content with two products containing vitamin E acetate rather than vitamin E succinate. Expected polyphenols were found in 7 of the 8 supplement products. None of the polyphenol supplements contained content within 100-120% of label claims. The present study indicates a lack of uniformity in nutraceutical products.

Keywords: content analysis; polyphenols; nutraceuticals; vitamin E succinate; pterostilbene; phloretin; myricetin

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MDPI and ACS Style

Remsberg, C.M.; Good, R.L.; Davies, N.M. Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals. Pharmaceutics 2010, 2, 50-60.

AMA Style

Remsberg C.M., Good R.L., Davies N.M. Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals. Pharmaceutics. 2010; 2(1):50-60.

Chicago/Turabian Style

Remsberg, Connie M.; Good, Renee L.; Davies, Neal M. 2010. "Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals." Pharmaceutics 2, no. 1: 50-60.

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