Next Article in Journal
A Recombinant HAV Expressing a Neutralization Epitope of HEV Induces Immune Response against HAV and HEV in Mice
Next Article in Special Issue
Tomato Leaf Curl New Delhi Virus: An Emerging Virus Complex Threatening Vegetable and Fiber Crops
Previous Article in Journal
Characterization of vB_SauM-fRuSau02, a Twort-Like Bacteriophage Isolated from a Therapeutic Phage Cocktail
Previous Article in Special Issue
Engineered Disease Resistance in Cotton Using RNA-Interference to Knock down Cotton leaf curl Kokhran virus-Burewala and Cotton leaf curl Multan betasatellite Expression
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessReview
Viruses 2017, 9(9), 256; doi:10.3390/v9090256

Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race

ICAR-Indian Institute of Soybean Research, Indian Council of Agricultural Research, Indore 452001, India
Department of Plant Pathology, Washington State University, Pullman, WA 99163, USA
National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi110067, India
Division of Plant Pathology, Advanced Centre for Plant Virology, ICAR-Indian Agricultural Research Institute (IARI), New Delhi 110012, India
Author to whom correspondence should be addressed.
Received: 30 June 2017 / Revised: 2 September 2017 / Accepted: 6 September 2017 / Published: 15 September 2017
(This article belongs to the Special Issue Geminiviruses)
View Full-Text   |   Download PDF [1119 KB, uploaded 15 September 2017]   |  


Geminiviruses are plant-infecting viruses characterized by a single-stranded DNA (ssDNA) genome. Geminivirus-derived proteins are multifunctional and effective regulators in modulating the host cellular processes resulting in successful infection. Virus-host interactions result in changes in host gene expression patterns, reprogram plant signaling controls, disrupt central cellular metabolic pathways, impair plant’s defense system, and effectively evade RNA silencing response leading to host susceptibility. This review summarizes what is known about the cellular processes in the continuing tug of war between geminiviruses and their plant hosts at the molecular level. In addition, implications for engineered resistance to geminivirus infection in the context of a greater understanding of the molecular processes are also discussed. Finally, the prospect of employing geminivirus-based vectors in plant genome engineering and the emergence of powerful genome editing tools to confer geminivirus resistance are highlighted to complete the perspective on geminivirus-plant molecular interactions. View Full-Text
Keywords: geminivirus; plant-virus interactions; cellular reprogramming; small non-coding RNAs; viral suppressors geminivirus; plant-virus interactions; cellular reprogramming; small non-coding RNAs; viral suppressors

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Ramesh, S.V.; Sahu, P.P.; Prasad, M.; Praveen, S.; Pappu, H.R. Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race. Viruses 2017, 9, 256.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top