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Viruses 2017, 9(3), 57; doi:10.3390/v9030057

Cross-Regulation between Transposable Elements and Host DNA Replication

Department of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, 604 Allison Rd, Nelson Biolabs A133, Piscataway, NJ 08854, USA
Academic Editors: David J. Garfinkel and Katarzyna J. Purzycka
Received: 1 February 2017 / Revised: 13 March 2017 / Accepted: 15 March 2017 / Published: 21 March 2017
View Full-Text   |   Download PDF [863 KB, uploaded 22 March 2017]   |  


Transposable elements subvert host cellular functions to ensure their survival. Their interaction with the host DNA replication machinery indicates that selective pressures lead them to develop ancestral and convergent evolutionary adaptations aimed at conserved features of this fundamental process. These interactions can shape the co-evolution of the transposons and their hosts. View Full-Text
Keywords: transposable elements; DNA replication; replication fork; transcription; genome integrity transposable elements; DNA replication; replication fork; transcription; genome integrity

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Zaratiegui, M. Cross-Regulation between Transposable Elements and Host DNA Replication. Viruses 2017, 9, 57.

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