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Viruses 2017, 9(1), 10; doi:10.3390/v9010010

Astrovirus Diagnostics

1,2
,
1,3,4
and
1,5,*
1
Institut Pasteur, Biology of Infection Unit, Inserm U1117, Laboratory of Pathogen Discovery, 75015 Paris, France
2
Institut Pasteur, Centre d’innovation et de Recherche Technologique (Citech), 75015 Paris, France
3
Paris Descartes University, Sorbonne Paris Cité, 75005, Paris, France
4
Necker-Enfants Malades University Hospital, Division of Infectious Diseases and Tropical Medicine, 75015 Paris, France
5
Ecole Nationale Vétérinaire d’Alfort, 94700 Maisons-Alfort, France
*
Author to whom correspondence should be addressed.
Academic Editor: Stacey Schultz-Cherry
Received: 22 November 2016 / Revised: 23 December 2016 / Accepted: 30 December 2016 / Published: 12 January 2017
(This article belongs to the Special Issue Astroviruses)
View Full-Text   |   Download PDF [335 KB, uploaded 12 January 2017]

Abstract

Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, novel human astrovirus (HAstV) strains have been found in immunocompromised individuals in association with central nervous system (CNS) infections. This work reviews the past and current methods for astrovirus detection and their uses in both research laboratories and for medical diagnostic purposes. View Full-Text
Keywords: astrovirus; virology; detection methods; molecular diagnostics astrovirus; virology; detection methods; molecular diagnostics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Pérot, P.; Lecuit, M.; Eloit, M. Astrovirus Diagnostics. Viruses 2017, 9, 10.

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