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Viruses 2015, 7(8), 4482-4487; doi:10.3390/v7082830

Special Issue: Gene Therapy with Emphasis on RNA Interference

PanTherapeutics, Rue des Remparts 4, CH1095 Lutry, Switzerland
Received: 29 July 2015 / Accepted: 4 August 2015 / Published: 6 August 2015
(This article belongs to the Special Issue Gene Therapy with Emphasis on RNA Interference)
View Full-Text   |   Download PDF [92 KB, uploaded 6 August 2015]

Abstract

Gene therapy was originally thought to cover replacement of malfunctioning genes in treatment of various diseases. Today, the field has been expanded to application of viral and non-viral vectors for delivery of recombinant proteins for the compensation of missing or insufficient proteins, anti-cancer genes and proteins for destruction of tumor cells, immunostimulatory genes and proteins for stimulation of the host defense system against viral agents and tumors. Recently, the importance of RNA interference and its application in gene therapy has become an attractive alternative for drug development. View Full-Text
Keywords: gene therapy; non-viral delivery; viral vectors; RNA interference gene therapy; non-viral delivery; viral vectors; RNA interference
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Lundstrom, K. Special Issue: Gene Therapy with Emphasis on RNA Interference. Viruses 2015, 7, 4482-4487.

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