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Viruses 2014, 6(11), 4258-4264; doi:10.3390/v6114258

Twenty Years of KSHV

Cancer Virology Program, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Pittsburgh, PA 15213, USA
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Received: 6 October 2014 / Revised: 29 October 2014 / Accepted: 30 October 2014 / Published: 7 November 2014
(This article belongs to the Special Issue Kaposi's Sarcoma-Associated Herpesvirus)
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Abstract

Twenty years ago, Kaposi’s sarcoma (KS) was the oncologic counterpart to Winston Churchill’s Russia: a riddle, wrapped in a mystery, inside an enigma. First described by Moritz Kaposi in 1872, who reported it to be an aggressive skin tumor, KS became known over the next century as a slow-growing tumor of elderly men—in fact, most KS patients were expected to die with the tumor rather than from it. Nevertheless, the course and manifestations of the disease varied widely in different clinical contexts. The puzzle of KS came to the forefront as a harbinger of the AIDS epidemic. The articles in this issue of Viruses recount progress made in understanding Kaposi’s sarcoma herpesvirus (KSHV) since its initial description in 1994. View Full-Text
Keywords: KSHV; Kaposi’s sarcoma; AIDS; virus discovery; history; viral oncogenesis KSHV; Kaposi’s sarcoma; AIDS; virus discovery; history; viral oncogenesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Chang, Y.; Moore, P. Twenty Years of KSHV. Viruses 2014, 6, 4258-4264.

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